We have since initiated over 15 discovery projects since the inception of Regor in June 2018. Our projects cover oncology, autoimmune and metabolic diseases areas with a strategy balance of Best-In-Class and First-In-Class programs. By fully leveraging our rCARD™ technology platform, we are able to deliver four PCCs within the range of 10-12 months from the initiation of each program.

Published Posters

Regor Next Generation CDK4 Inhibitor RGT-419B SABCS 2023 Poster Presentation
First-in-human Phase 1A study of RGT-419B, a next generation CDK4 inhibitor, in patients (pts) with HR+/HER2- ABC who progressed on prior CDK4/6 inhibitors

Regor PAD4 inhibitor QR-6691 ACR 2023 Poster Presentation
Discovery and Characterization of a Selective, Orally Bioavailable PAD4 Inhibitor to Target NETs Driven Autoimmune and Inflammatory Diseases

Regor STING inhibitor RGT-118 ACR 2023 Oral Presentation
Autoimmune Pathway Blockade by a Potent Orally Bioavailable STING Antagonist

Regor SOS1 Inhibitor RGT-018 AACR 2023 Poster Presentation
Discovery of Potent, Selective and Orally Bioavailable SOS1 Inhibitors for KRAS-Driven Cancers

Regor GLP1 Preclinical and Clinical Presentations at ADA 2022 Meeting

  1. RGT-075, An Orally Efficacious Small Molecule GLP-1R Full Agonistin Cynomolgus Monkey Models
  2. A First-in-Human Study of RGT-075, a Novel, Orally Bioavailable, Small-Molecule GLP-1 Receptor Agonist, in Healthy Adult Subjects
  3. A Phase 1, Double-Blind, Placebo-Controlled Multiple Escalating Dose Study of RGT-075, a Novel Small-Molecule Oral GLP-1 Receptor Agonist in Adults with Type 2 Diabetes

Regor HPK1 Inhibitor AACR EORTC 2021 Poster Presentation
Discovery of A Highly Potent HPK1 Inhibitor That Augments Immune Activation and Anti-tumor Immunity

Regor CDK Inhibitor RGT 419B SABCS 2020 Poster Presentation
Targeting Resistance to Current CDK4/6 Therapies by RGT-419B, an Inhibitor with an Optimized Kinase Activity Spectrum

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